This file contains detailed descriptions of all the dataset files 1) 01-SNVs.vcf.gz This file contains the SNVs of 'Golden Delicious' and 'Jonathan' 2) 02-SVs.gz This file contains the genotype of all the structure variation of 'Golden Delicious' and 'Jonathan' 3) 03-KASP genotyping dataset.XLSX This file contains two sheets: sheet1: Kompetitive allele-specific PCR (KASP) genotyping of the candidate variations in extreme bulks samples sheet2: KASP genotyping of extremes accessions on candidate variations 4) 04-RNA-seq expression data used in the meta-analysis.XLSX The highest expression (FPKM) of all the fruit samples from SRA used in the meta-analysis 5) 05-RNA-seq_DEGs.XLSX The different expression gene dataset used in the candidate gene screening process From left column to righ column£º 1. Transcript name 2. log2Changfold of S1/R1 3. log2Changfold of S2/R2 4. log2Changfold of S3/R3 5. Gene 6. Gene annotation 6) 06-Expression quantity of RNA-Seq.XLSX The expression FPKM matrix of all the individuals in this study 7) 07-Sanger sequencing.pdf Sequence alignment of candidate genes of¡®Jonathan', ¡®Golden Delicious' (GD), and the apple reference genome (DH). 8) 08-code.txt 1) The R code used in the G value analysis, G' value analysis and threshold selection process 2) The R code used to calculate the euclidean distance (ED), SNP index (SI) 9) 09-Zz26_counts_genotype.txt The count with different genotype allele in coupled extreme bulks resistant/susceptible to isolate Zz26 From left column to righ column£º 1. Chrom: the chromosome of the variation 2. Pos: the positon of the variation in the chromosome 3. R_Ref: read counts with the reference genotype in Resistant bulk 4. R_Alt: read counts with the alter genotype in Resistant bulk 5. S_Ref: read counts with the reference genotype in Susceptible bulk 6. S_Alt: read counts with the alter genotype in Susceptible bulk 7. G_value: G value 8. Gp_value: Gp value 9. Type: the type of the variation [G/J/H] 10) 10-Ls1_counts_genotype.txt The count with different genotype allele in coupled extreme bulks resistant/susceptible to isolate Ls1 From left column to righ column£º 1. Chrom: the chromosome of the variation 2. Pos: the positon of the variation in the chromosome 3. R_Ref: read counts with the reference genotype in Resistant bulk 4. R_Alt: read counts with the alter genotype in Resistant bulk 5. S_Ref: read counts with the reference genotype in Susceptible bulk 6. S_Alt: read counts with the alter genotype in Susceptible bulk 7. G_value: G value 8. Gp_value: Gp value 9. Type: the type of the variation [G/J/H] 11) 11-Lw023_counts_genotype.txt The count with different genotype allele in coupled extreme bulks resistant/susceptible to Lw023 From left column to righ column£º 1. Chrom: the chromosome of the variation 2. Pos: the positon of the variation in the chromosome 3. R_Ref: read counts with the reference genotype in Resistant bulk 4. R_Alt: read counts with the alter genotype in Resistant bulk 5. S_Ref: read counts with the reference genotype in Susceptible bulk 6. S_Alt: read counts with the alter genotype in Susceptible bulk 7. G_value: G value 8. Gp_value: Gp value 9. Type: the type of the variation [G/J/H] 12) 12-Lw048_counts_genotype.txt The count with different genotype allele in coupled extreme bulks resistant/susceptible to Lw048 From left column to righ column£º 1. Chrom: the chromosome of the variation 2. Pos: the positon of the variation in the chromosome 3. R_Ref: read counts with the reference genotype in Resistant bulk 4. R_Alt: read counts with the alter genotype in Resistant bulk 5. S_Ref: read counts with the reference genotype in Susceptible bulk 6. S_Alt: read counts with the alter genotype in Susceptible bulk 7. G_value: G value 8. Gp_value: Gp value 9. Type: the type of the variation [G/J/H] 13) 13-Haplotype block data of 'Golden Delicious' The haplotype block data constructed by using reads from 'Golden Delicious' From left column to righ column£º 1. Chrom: the chromosome of the haplotype block 2. Start: the start of the haplotype block 3. Pos: the position of the variation 4. Blockname: the haplotype block name 5. M: like output from samtools phase 6. Ref: the reference allele 7. Block1: the allele in haplotype block1 8. Block2: the allele in haplotype block2 14) 14-haplotype block data of 'Jonathan' The haplotype block data contructed by using reads from 'Jonathan' From left column to righ column£º 1. Chrom: the chromosome of the haplotype block 2. Start: the start of the haplotype block 3. Pos: the position of the variation 4. Blockname: the haplotype block name 5. M: like output from samtools phase 6. Ref: the reference allele 7. Block1: the allele in haplotype block1 8. Block2: the allele in haplotype block2 15£©15-RNA-Seq_variations The variations and annotation identified from the RNA-Seq samples. 16£©16-phenotype.XLSX The phenotype data of the individuals in each extreme bulk Table 1. The lesion length of five years of individuals in extreme bulk resistant to isolate Lw023 Table 2. The lesion length of five years of individuals in extreme bulk susceptible to isolate Lw023 Table 3. The lesion length of five years of individuals in extreme bulk resistant to isolate Lw048 Table 4. The lesion length of five years of individuals in extreme bulk susceptible to isolate Lw048 Table 5. The lesion length of five years of individuals in extreme bulk resistant to isolate Zz26 Table 6. The lesion length of five years of individuals in extreme bulk susceptible to isolate Zz26 Table 7. The lesion length of five years of individuals in extreme bulk resistant to isolate Ls1 Table 8. The lesion length of five years of individuals in extreme bulk susceptible to isolate Ls1 17£© 17-functional domain datasets The functional domain datasets From left column to righ column£º Chrom£º Chromosome Pos£º the SNP position in the chromosome Gene£º the gene name G_POS: the SNP position in the gene domain: the name of the functional domain 18£©18-CRE.bed cis-regulatory element in the promoter regions