Table S5. GO enrichment for genes under selection. This is the GOstats output for enrichment tests of the set of genes under positive selection in N. melanderi. GO ID Pvalue OddsRatio ExpCount Count Size Term p_adj GO category GO:0004828 0.002144168 Inf 0.092778071 2 2 serine-tRNA ligase activity 0.017212792 Molecular Function GO:0003924 0.002502843 2.823809524 4.731681603 12 102 GTPase activity 0.017212792 Molecular Function GO:0017111 0.002506987 1.865402983 17.58144439 30 379 nucleoside-triphosphatase activity 0.017212792 Molecular Function GO:0016462 0.003056511 1.837244676 17.81338956 30 384 pyrophosphatase activity 0.017212792 Molecular Function GO:0016818 0.003303547 1.826202823 17.90616763 30 386 hydrolase activity acting on acid anhydrides in phosphorus-containing anhydrides 0.017212792 Molecular Function GO:0035639 0.003413812 1.593317309 35.25566684 51 760 purine ribonucleoside triphosphate binding 0.017212792 Molecular Function GO:0032555 0.003508784 1.590735965 35.30205588 51 761 purine ribonucleotide binding 0.017212792 Molecular Function GO:0017076 0.003606044 1.588161883 35.34844491 51 762 purine nucleotide binding 0.017212792 Molecular Function GO:0016817 0.003849066 1.804487179 18.09172377 30 390 hydrolase activity acting on acid anhydrides 0.017212792 Molecular Function GO:0032553 0.003911998 1.580482897 35.48761202 51 765 ribonucleotide binding 0.017212792 Molecular Function GO:0003824 0.004809833 1.398271799 109.1534001 130 2353 catalytic activity 0.019239334 Molecular Function GO:0004579 0.00623501 41.41984733 0.139167106 2 3 dolichyl-diphosphooligosaccharide-protein glycotransferase activity 0.022861704 Molecular Function GO:0097367 0.009296733 1.492511946 37.94623089 52 818 carbohydrate derivative binding 0.031465867 Molecular Function GO:0016757 0.010371355 2.701008403 3.66473379 9 79 transferase activity transferring glycosyl groups 0.032595686 Molecular Function GO:0051920 0.012088625 20.70610687 0.185556141 2 4 peroxiredoxin activity 0.035459967 Molecular Function GO:0016758 0.014135565 2.989438577 2.597785978 7 56 transferase activity transferring hexosyl groups 0.038872804 Molecular Function GO:0016787 0.016509061 1.417040064 43.6056932 57 940 hydrolase activity 0.039294072 Molecular Function GO:0004576 0.019533878 13.80152672 0.231945177 2 5 oligosaccharyl transferase activity 0.039294072 Molecular Function GO:0004197 0.019970662 6.226436782 0.603057459 3 13 cysteine-type endopeptidase activity 0.039294072 Molecular Function GO:1901265 0.024369498 1.401248399 39.10595677 51 843 nucleoside phosphate binding 0.039294072 Molecular Function GO:0000166 0.024369498 1.401248399 39.10595677 51 843 nucleotide binding 0.039294072 Molecular Function GO:0004298 0.024562845 5.659352142 0.649446494 3 14 threonine-type endopeptidase activity 0.039294072 Molecular Function GO:0070003 0.024562845 5.659352142 0.649446494 3 14 threonine-type peptidase activity 0.039294072 Molecular Function GO:0043168 0.028246058 1.368790962 43.97680548 56 948 anion binding 0.039294072 Molecular Function GO:0003735 0.02908466 2.118826056 5.05640485 10 109 structural constituent of ribosome 0.039294072 Molecular Function GO:0005525 0.029766297 1.900149402 7.283078545 13 157 GTP binding 0.039294072 Molecular Function GO:0032561 0.029766297 1.900149402 7.283078545 13 157 guanyl ribonucleotide binding 0.039294072 Molecular Function GO:0032550 0.029766297 1.900149402 7.283078545 13 157 purine ribonucleoside binding 0.039294072 Molecular Function GO:0032549 0.029766297 1.900149402 7.283078545 13 157 ribonucleoside binding 0.039294072 Molecular Function GO:0001883 0.029766297 1.900149402 7.283078545 13 157 purine nucleoside binding 0.039294072 Molecular Function GO:0019001 0.029766297 1.900149402 7.283078545 13 157 guanyl nucleotide binding 0.039294072 Molecular Function GO:0005524 0.029877264 1.444057037 28.01897733 38 604 ATP binding 0.039294072 Molecular Function GO:0032559 0.030560868 1.441213654 28.06536637 38 605 adenyl ribonucleotide binding 0.039294072 Molecular Function GO:0001882 0.031138712 1.886687732 7.32946758 13 158 nucleoside binding 0.039294072 Molecular Function GO:0030554 0.031256648 1.438380282 28.1117554 38 606 adenyl nucleotide binding 0.039294072 Molecular Function GO:0008094 0.035300466 4.786914235 0.742224565 3 16 DNA-dependent ATPase activity 0.043145014 Molecular Function GO:0004089 0.046389035 Inf 0.046389035 1 1 carbonate dehydratase activity 0.046389035 Molecular Function GO:0003980 0.046389035 Inf 0.046389035 1 1 UDP-glucose:glycoprotein glucosyltransferase activity 0.046389035 Molecular Function GO:0070569 0.046389035 Inf 0.046389035 1 1 uridylyltransferase activity 0.046389035 Molecular Function GO:2001070 0.046389035 Inf 0.046389035 1 1 starch binding 0.046389035 Molecular Function GO:0008108 0.046389035 Inf 0.046389035 1 1 UDP-glucose:hexose-1-phosphate uridylyltransferase activity 0.046389035 Molecular Function GO:0004853 0.046389035 Inf 0.046389035 1 1 uroporphyrinogen decarboxylase activity 0.046389035 Molecular Function GO:0000030 0.046389035 Inf 0.046389035 1 1 mannosyltransferase activity 0.046389035 Molecular Function GO:0031491 0.046389035 Inf 0.046389035 1 1 nucleosome binding 0.046389035 Molecular Function GO:0098687 6.35E-05 42.15929204 0.280687725 4 6 chromosomal region 0.000834785 Cellular Component GO:0000775 6.35E-05 42.15929204 0.280687725 4 6 chromosome centromeric region 0.000834785 Cellular Component GO:0043228 8.35E-05 2.607317073 12.77129148 27 273 non-membrane-bounded organelle 0.000834785 Cellular Component GO:0043232 8.35E-05 2.607317073 12.77129148 27 273 intracellular non-membrane-bounded organelle 0.000834785 Cellular Component GO:0043234 0.000511182 2.488047705 10.52578968 22 225 protein complex 0.004089459 Cellular Component GO:0032991 0.001259449 1.973078693 21.47261096 35 459 macromolecular complex 0.008396324 Cellular Component GO:0008290 0.002170652 Inf 0.093562575 2 2 F-actin capping protein complex 0.011970987 Cellular Component GO:0044424 0.002394197 1.739534703 45.79888045 61 979 intracellular part 0.011970987 Cellular Component GO:0044422 0.003465958 2.060928433 12.91163535 23 276 organelle part 0.013863833 Cellular Component GO:0044446 0.003465958 2.060928433 12.91163535 23 276 intracellular organelle part 0.013863833 Cellular Component GO:0000502 0.005347037 6.997050147 0.7485006 4 16 proteasome complex 0.017823456 Cellular Component GO:1905369 0.005347037 6.997050147 0.7485006 4 16 endopeptidase complex 0.017823456 Cellular Component GO:0005623 0.009056043 1.654105064 71.52858856 84 1529 cell 0.025874408 Cellular Component GO:0044464 0.009056043 1.654105064 71.52858856 84 1529 cell part 0.025874408 Cellular Component GO:0043226 0.010991121 1.595003603 36.11515394 48 772 organelle 0.027477802 Cellular Component GO:0043229 0.010991121 1.595003603 36.11515394 48 772 intracellular organelle 0.027477802 Cellular Component GO:1905368 0.012315411 5.238938053 0.93562575 4 20 peptidase complex 0.028127121 Cellular Component GO:0044430 0.012657204 2.842813456 3.181127549 8 68 cytoskeletal part 0.028127121 Cellular Component GO:0005783 0.013593302 3.428780131 2.011595362 6 43 endoplasmic reticulum 0.028274439 Cellular Component GO:0005622 0.014356294 1.581428571 69.28308677 81 1481 intracellular 0.028274439 Cellular Component GO:0031227 0.016105724 6.944444444 0.56137545 3 12 intrinsic component of endoplasmic reticulum membrane 0.028274439 Cellular Component GO:0012505 0.016149066 2.530701754 3.976409436 9 85 endomembrane system 0.028274439 Cellular Component GO:0044427 0.0168337 3.25017325 2.105157937 6 45 chromosomal part 0.028274439 Cellular Component GO:0005694 0.016964664 2.911051693 2.713314674 7 58 chromosome 0.028274439 Cellular Component GO:0005839 0.024890536 5.677033493 0.654938025 3 14 proteasome core complex 0.039824857 Cellular Component GO:0005840 0.030477357 2.134579439 5.145941623 10 110 ribosome 0.046888242 Cellular Component GO:0005737 0.034763046 1.555773488 20.06917233 28 429 cytoplasm 0.047980808 Cellular Component GO:0015629 0.039063526 3.480825959 1.30987605 4 28 actin cytoskeleton 0.047980808 Cellular Component GO:0030529 0.039622408 1.957861635 6.128348661 11 131 intracellular ribonucleoprotein complex 0.047980808 Cellular Component GO:1990904 0.039622408 1.957861635 6.128348661 11 131 ribonucleoprotein complex 0.047980808 Cellular Component GO:0005789 0.04372884 3.340176991 1.356657337 4 29 endoplasmic reticulum membrane 0.047980808 Cellular Component GO:0098827 0.04372884 3.340176991 1.356657337 4 29 endoplasmic reticulum subcompartment 0.047980808 Cellular Component GO:0042175 0.04372884 3.340176991 1.356657337 4 29 nuclear outer membrane-endoplasmic reticulum membrane network 0.047980808 Cellular Component GO:0005856 0.043831154 2.076086957 4.724910036 9 101 cytoskeleton 0.047980808 Cellular Component GO:0072588 0.046781287 Inf 0.046781287 1 1 box H/ACA RNP complex 0.047980808 Cellular Component GO:0031429 0.046781287 Inf 0.046781287 1 1 box H/ACA snoRNP complex 0.047980808 Cellular Component GO:0005869 0.046781287 Inf 0.046781287 1 1 dynactin complex 0.047980808 Cellular Component GO:0008250 0.046781287 Inf 0.046781287 1 1 oligosaccharyltransferase complex 0.047980808 Cellular Component GO:0044452 0.046781287 Inf 0.046781287 1 1 nucleolar part 0.047980808 Cellular Component GO:0044432 0.048694592 3.210347175 1.403438625 4 30 endoplasmic reticulum part 0.048694592 Cellular Component