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Rahman et al_Supplementary_G3_11112019.pdf (1.15 MB)

Supplemental Material for Rahman et al., 2020

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posted on 2019-11-22, 17:02 authored by Hadiar Rahman, Andrew Rudrow, Joshua carneglia, Sister Stephen Patrick Joly, Dante Nicotera, Michael Naldrett, John Choy, Suresh V. Ambudkar, John Golin

Nonsynonymous Mutations in Linker-2 increase mRNA stability by increasing half-life. Thus, enhance drug resistance compare to the Wild type strain.

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Article title

Nonsynonymous Mutations in Linker-2 of the Pdr5 Multidrug Transporter Identify a New RNA Stability Element

Manuscript #

G3/2019/400863-TR1

Article DOI

10.1534/g3.119.400863

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    G3: Genes|Genomes|Genetics

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    Keywords

    ABC tranporternonsynonymous mutationmRNAPdr5drug resistanceGeneticsGene Expression (incl. Microarray and other genome-wide approaches)GenomicsGenome Structure and RegulationMicrobiologyMolecular Biology

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    CC BY 4.0

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