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Supplemental Material for Corda et al., 2021

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posted on 14.12.2020, 18:46 by Yves Corda, Laetitia Maestroni, Pierre Luciano, Maria Y. Najem, Vincent Géli
Supplemental Materials: Table S1. Strains used in this study; Figure S1. RTT105 is required for normal cell growth; Figure S2. RTT105 exhibits genetic interactions with S-phase checkpoint components; Figure S3.RTT105 is important for cells affected in the replication-dependent nucleosome assembly process; Figure S4.RTT105 is important for cells affected in the replication-dependent nucleosome assembly process but not in replication-independent nucleosome assembly; Figure S5. RTT105 inactivation exacerbates the telomeric defects arising in absence of YKU and EST1 genes; Figure S6. RTT105 inactivation affects senescence and survivor formation in est1∆ cells; Figure S7. Exogenous expression of rtt105∆155-208 mutant failed to rescue the growth in rtt105∆ cells; Figure S8. Cell cycle regulation of CLB2-rfa1; Figure S9. Bringing Rfa1 into the nucleus rescues the viability of rfa1∆ and rfa1-D228Y rtt105∆ cells but not the growth defect and HU sensitivity in rtt105∆ cells; Figure S10. Bringing Rfa1 into the nucleus rescues the growth of rtt105∆ cells affected in S-phase checkpoint, cohesion, or repair.

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Article title

Genome stability is guarded by yeast Rtt105 through multiple mechanisms

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GENETICS/2020/303800R2

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