Supplementary material for Scott et al., 2018

dataset

posted on 2018-12-04, 14:41 authored by Benjamin M. Scott, Steven K. Chen, Nihar Bhattacharyya, Abdiwahab Y. Moalim, Sergey V. Plotnikov, Elise Heon, Sergio G. Peisajovich, Belinda S.W. Chang

File S1.txt is the pipeline for Fiji to identify yeast cell outlines.

File S2.m is the pipeline for MATLAB to identify fluorescent patches on yeast cell membranes.

Figure S5 Snake plot of human rhodopsin mutations investigated in this study.

Table S2 Light activation of yeast-expressed rhodopsin compared to previous studies. Includes raw fluorescent reporter gene values for light-activated and dark state yeast-expressed rhodopsin.

"Supplemental Figures and Tables for Scott et al. 2018" contains Figures S1, S2, S3, S4, S6, S7, S8, S9, S10 and Tables S1, S3

History

Article title

Coupling of Human Rhodopsin to a Yeast Signaling Pathway Enables Characterization of Mutations Associated with Retinal Disease

Manuscript #

GENETICS/2018/301733

Article DOI

10.1534/genetics.118.301733

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Keywords

G protein-coupled receptor rhodopsin retinitis pigmentosa disease model synthetic biology snake plot MATLAB pipeline Medical Genetics (excl. Cancer Genetics)Genetics Ophthalmology Synthetic Biology

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CC BY 4.0

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