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Supplementary Material for Wernick et al. 2019
dataset
posted on 2019-02-05, 19:14 authored by Riana I. Wernick, Stephen F. Christy, Dana K. Howe, Jennifer A. Sullins, Joseph F. Ramirez, Maura Sare, McKenna J. Penley, Levi T. Morran, Dee R. Denver, Suzanne EstesSupplementary figures show the following; S1 and S2:
relative and competitive fitness of gas-1
RC lines, respectively; S3: normalized mtDNA copy number for all C. elegans lines; S4: expected and
observed percentages of gas-1 RC line
genic mtDNA mutations; S5: chromatograms depicting evolutionary trajectories of
two mtDNA variants; S6: GO enrichments and interactome results for gas-1 RC line mutations; S7: GO term
categorizations for gas-1 RC line
SNPs.
Supplementary tables contain the following data; S1: Illumina HiSeq run
statistics; S2: ANOVA results for C.
elegans life-history traits; S3: results of mtDNA copy number
normalization; S4: gas-1 G0 mutations
reverted to wildtype alleles within RC lines; S5: mtDNA SNPs; S6: nDNA SNPs;
S7: gas-1 RC line SNPs occurring
within the gas-1 interactome.
File S1
shows the frequencies within each gas-1 RC
line for all mtDNA positions in which a variant was identified.
File S2 shows
the frequencies within each gas-1 MA
line for the fox-1 single-basepair reversion
discovered within three gas-1 RC
lines.
File S3 contains custom code for simulations reported in Figure S5.
File
S4 contains a complete accounting of gas-1
RC G0 enrichment results.
