posted on 2020-05-01, 14:22authored byAiping Zhou, Jun Li, Zhihong Xue, Jinjing Ni, Jian. Guo, Yu-Feng Yao, Wenjuan Wu
Salmonellaenterica serovar
Rissen (S. Rissen) is a widely distributed serotype; however,
its virulence and pathogenicity are poorly understood. In this study, the
pathogenicity and antibiotic resistance of a representative S. Rissen isolate was
investigated. The cell model showed that S. Rissen preferred to
replicate in human macrophage cells U937 compared to murine macrophage cells
RAW264.7, suggesting that it has a level of host adaptability. Genome
sequencing and comparison analysis revealed that the distribution and
nonsynonymous single nucleotide polymorphisms of virulence factors in S. Rissen were similar
to those in S. Typhi rather than to those in S. Typhimurium.
History
Article title
Whole-Genome Comparative and Pathogenicity Analysis of Salmonella enterica subsp. enterica Serovar Rissen