Supplemental Material for Siebert et al., 2022
This data set represents the results of RNA-seq transcriptome analysis for the submitted revised manuscript entitled: Genetic Analysis of Human RNA Binding Motif Protein 48 (RBM48) Reveals an Essential Role in U12-Type Intron Splicing
Dataset S1. Read counts and statistics for individual introns and exon-exon junctions
detected in RNA-seq experiments. Intron coordinates are given for the Homo_sapiens.GRCh38.87
reference genome annotation. Intron reads and exon-exon junction reads are summed by Vector Control
(VC) and Knockout (KO) K-562 sublines for all biological replicates. Introns were filtered for overlap with
the MIDB dataset (see RNA-seq Methods in main article). Prior to analysis, introns were filtered for a
minimum sum of 10 total exon-exon junction and intronic read counts with an intronic density (Di) > 0 in
both VC or KO populations.
Dataset S2. Read counts for individual introns and exon-exon junctions for each biological
replicate from Vector Control (VC) and Knockout (KO) K-562 sublines detected in RNA-seq experiments.