Supplemental Material for Mutlu et al., 2019
datasetposted on 2019-08-27, 15:05 authored by Nebibe Mutlu, Daniel Sheidy, Angela Hsu, Han Jeong, Katherine Wozniak, Anuj Kumar
File S1 contains detailed descriptions of all supplemental files. File S2 contains statistical analysis of all changes in transcript abundance, both significant and insignificant, between the ksp1-K47D mutant and wild type as determined using DESeq2. File S3 contains boxplots indicating non-normalized counts, depth-normalized counts, and regularized Log 2-normalized counts for each RNA-Seq sample analyzed. File S4 contains statistical analysis of all changes in transcript abundance, both significant and insignificant, between the ksp1-K47D mutant and wild type as determined using Tuxedo. File S5 presents summary boxplots of FPKM (Fragments Per Kilobase of transcript per Million mapped reads) distribution in Log 10 scale for each RNA sample. File S6 provides a listing of the union set of genes identified as undergoing statistically significant changes in transcript abundance between ksp1-K47D and wild type by both DESeq2 and Tuxedo analysis. File S7 provides the mass spectrometry data from Mascot and MaxQuant analysis for differentially abundant phosphopeptides between ksp1-K47D and wild type. File S8 provides the protein-protein interactions extracted from BioGRID.