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File S1_ Caenorhabditis_HLH12.fa (6.4 kB)
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File S2_Nematode_bHLH-protein_sequences.fa (55.96 kB)
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Supplemental Material for Littleford, et al., 2021

dataset
posted on 2021-08-03, 15:44 authored by Hana E. Littleford, Karin KiontkeKarin Kiontke, David H. A. Fitch, Iva Greenwald
Figure S1 contains further data on the consequence of ectopic expression of HLH-12 in the AC.
Figure S2 contains a detailed schematic of bins used to determine statistical significance of AC displacement in

Figure 2 and results of RNAi experiments.

Figure S3 contains a phylogeny of 41 C. elegans bHLH proteins obtained with Bayesian inference analysis.

Figure S4 contains phylograms for the large and small bHLH domain sequence dataset and three different alignments.

Figure S5 shows the presence of hlh-12 and its probable genomic location mapped onto the Caenorhabditis phylogeny.

History

Article title

hlh-12, a gene that is necessary and sufficient to promote migration of gonadal regulatory cells in C. elegans, evolved within the Caenorhabditis clade