Supplemental Material for Kawamura and Maruyama, 2019
datasetposted on 25.06.2019 by Kazuto Kawamura, Ichiro N Maruyama
Datasets usually provide raw data for analysis. This raw data often comes in spreadsheet form, but can be any collection of data, on which analysis can be performed.
Fig S1. Photos of Edge Assay; Table S1. Number of screened genomes and isolated mutants; Fig S2. Maximum velocity and travel distance of isolated mutants; Fig S3. ix241 and ix243 worms show progressive locomotor decline after four backcrosses; Table S2. Lifespan Analysis; Fig S4. Greater reduction in total locomotor healthspan compared to lifespan in ix243 worms; Table S3. Development times of isolated mutant strains; Fig S5. Strategy to identify causative mutation site; Table S4. Remaining mutations in ix243 mutant strains; Fig S6. Wild-type elpc-2 gene rescues progressive decline in locomotor ability of the ix243 mutant strain; Fig S7. The Elongator complex is required to maintain adult locomotor ability; Fig S8. Expression pattern of elpc-2 transcriptional GFP fusion; Fig S9. tut-1(tm1297) mutant shows progressive decline in locomotor ability; Table S5. Development times of tut-1(tm1297) and elpc-2(ix243);tut-1(tm1297) mutants; Fig S10. Amino acid alignment of C. elegans ELPC-2 and human ELP2; Table S6. Strain list; Table S7. Primer list.
Figure legends and descriptions of tables are shown in "Description of Supplementary figures and tables.docx".