Supplemental Material for Jain, 2019

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Figure S1: Fixation probability for N = 6 × 10⁵ when the beneficial effect s_b is varied. The other parameters are s_d = 0.01 (top) and 0.002 (bottom) with u_d = 5s_d, U_d = u_d. The data from stochastic simulations (•) with errorbars representing the standard deviation, and by numerically calculating (1) (◦) and (5) (△) are shown.

Figure S2: Fixation probability for N = 6 × 10⁵ when the beneficial effect s_b is varied. The other parameters are s_d = 0.01, u_d = 5s_d, U_d = 2u_d (top) and s_d = 0.002, u_d = 5s_d, U_d = 5u_d (bottom). The data from stochastic simulations (•) with errorbars representing the standard deviation, and by numerically calculating (1) (◦) and (5) (△) are shown.

Figure S3: Expected substitution rate E[k_b] and average fixed selection co-efficient E[s_b] for N = 2 × 10⁵ when the average beneficial effect s¯_b is varied. The other parameters are s_d = 0.01, u_d = 5s_d, u_b = 5 × 10⁻⁷. The data from numerical simulations (•) and numerical integration of (12) and (17) using quadratic approximation (5) (⊕) and analytical expression (9) (◦) are shown.