1/1
0/0

Supplemental Material for Hamza et al., 2020

dataset
posted on 14.01.2020 by Akil Hamza, Maureen R.M. Driessen, Erik Tammpere, Nigel J. O'Neil, Philip Hieter

Figure S1 contains complementation assays for the nonessential CIN genes. Figure S2 contains complementation assays of two-subunit yeast complexes. Figure S3 contains growth curve assays for testing hFEN1 inhibitors in MMS. Figure S4 contains growth curve assays for testing hFEN1 inhibitors in HR-deficient strains. Figure S5 contains growth curve assays assessing overexpression of hFEN1 in yeast. Table S1 lists primers used for CRISPR-mediated insertion and deletion. Table S2 lists plasmids and strains used in study. Table S3 lists all candidate complementation pairs tested in study. Table S4 compares our list of complementation pairs to literature sources.

History

Article title

Cross-Species Complementation of Nonessential Yeast Genes Establishes Platforms for Testing Inhibitors of Human Proteins

Manuscript #

GENETICS/2019/302971R1

Article DOI

10.1534/genetics.119.302971

Licence

Exports