DOCUMENT
Figure S1.pdf (342.22 kB)
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Figure S2.pdf (105.04 kB)
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Figure S3.pdf (120.32 kB)
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Figure S4.pdf (104.26 kB)
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Figure S5.pdf (68.22 kB)
DATASET
Table S1.xlsx (11.59 kB)
DATASET
Table S2.xlsx (10.57 kB)
DATASET
Table S3.xlsx (20.25 kB)
DATASET
Table S4.xlsx (10.78 kB)
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Supplemental Material for Hamza et al., 2020
dataset
posted on 2020-01-14, 19:17 authored by Akil Hamza, Maureen R.M. Driessen, Erik Tammpere, Nigel J. O'Neil, Philip HieterFigure S1 contains complementation assays for the nonessential CIN genes. Figure S2 contains complementation assays of two-subunit yeast complexes. Figure S3 contains growth curve assays for testing hFEN1 inhibitors in MMS. Figure S4 contains growth curve assays for testing hFEN1 inhibitors in HR-deficient strains. Figure S5 contains growth curve assays assessing overexpression of hFEN1 in yeast. Table S1 lists primers used for CRISPR-mediated insertion and deletion. Table S2 lists plasmids and strains used in study. Table S3 lists all candidate complementation pairs tested in study. Table S4 compares our list of complementation pairs to literature sources.
