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Supplemental Material for Delaney et. al., 2018
dataset
posted on 2018-04-10, 16:42 authored by Kamila Delaney, Jonathan Mailler, Joanna M. Wenda, Caroline Gabus, Florian A. SteinerFigure
S1 shows an analysis of C. elegans
H3.3 homologues. Figure S2 contains a summary of deletion and mutation alleles.
Figure S3 contains
correlation plots of biological replicates for the RNA-seq experiments. Figure
S4 shows H3.3 homologue expression during embryogenesis. Figure S5 shows H3.3
homologue expression in the hermaphrodite and male germ line. Figure S6 shows
comparison of expression levels of H3.3 homologues. Figure S7 shows that
H3.3 proteins are depleted from chromosome X. Figure S8 shows alignment of C. elegans HIRA-1 with homologues from
other species. Figure S9 shows morphological
defects and reduced brood size of hira-1 mutant worms. Figure S10 shows
that HIS-71 and HIS-72 are detectable in the postembryonic somatic tissue even
upon hira-1 deletion. Figure S11
shows embryonic lethality and apoptosis in H3.3 null mutant worms. Figure
S12 shows the identity and expression of additional H3 homologues in C. elegans. Table S1 lists the C. elegans strains used in this study.
Table S2 lists the reagents used for allele generation by CRISPR/Cas9 and
quantitative PCR. Table S3 contains the RNA-seq results for embryos. Table S4 contains
the RNA-seq results for L1 larvae. Table S5 lists all significantly enriched GO
terms.