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Supplemental Material for Cherian, Adams, and Petrella, 2020

dataset
posted on 16.12.2019, 16:30 by Jerrin Cherian, Katherine Adams, Lisa N. Petrella

Figure S1 contains HTA suppression data for TF knockdown in lin-54 mutants for TF candidates that passed the preliminary binary qualitative screen but failed the quantitative analysis. Figure S2 contains distribution of adjusted PGL-1 intensity data for wild type and lin-54 mutant controls at both 20°C and 26°C. Figure S3 contains Quantification of Wnt ligand EGL-20 localization in lin-54 mutants. Table S1 contains the list of TFs with DREAM target loci binding information. Table S2 shows a list of transcription factors tested for suppression of HTA phenotype in lin-54 mutants and the TF families. Table S3 contains a list of enriched GO terms, Wiki Pathway terms and TransFac terms determined using gProfiler for TFs that show significant suppression of the HTA phenotype in lin-54 mutants. Table S4 contains a list of enriched GO terms determined using PANTHER Overrepresentation test for TFs that show significant suppression of the HTA phenotype in lin-54 mutants. Table S5 contains a list of Wnt signaling genes that were tested for suppression of HTA phenotype in lin-54 mutants.

History

Article title

Wnt Signaling Drives Ectopic Gene Expression and Larval Arrest in the Absence of the Caenorhabditis elegans DREAM Repressor Complex

Manuscript #

G3/2019/400850

Article DOI

10.1534/g3.119.400850