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Supplemental Material for Cherian, Adams, and Petrella, 2020

dataset
posted on 16.12.2019 by Jerrin Cherian, Katherine Adams, Lisa N. Petrella

Figure S1 contains HTA suppression data for TF knockdown in lin-54 mutants for TF candidates that passed the preliminary binary qualitative screen but failed the quantitative analysis. Figure S2 contains distribution of adjusted PGL-1 intensity data for wild type and lin-54 mutant controls at both 20°C and 26°C. Figure S3 contains Quantification of Wnt ligand EGL-20 localization in lin-54 mutants. Table S1 contains the list of TFs with DREAM target loci binding information. Table S2 shows a list of transcription factors tested for suppression of HTA phenotype in lin-54 mutants and the TF families. Table S3 contains a list of enriched GO terms, Wiki Pathway terms and TransFac terms determined using gProfiler for TFs that show significant suppression of the HTA phenotype in lin-54 mutants. Table S4 contains a list of enriched GO terms determined using PANTHER Overrepresentation test for TFs that show significant suppression of the HTA phenotype in lin-54 mutants. Table S5 contains a list of Wnt signaling genes that were tested for suppression of HTA phenotype in lin-54 mutants.

History

Article title

Wnt Signaling Drives Ectopic Gene Expression and Larval Arrest in the Absence of the Caenorhabditis elegans DREAM Repressor Complex

Manuscript #

G3/2019/400850

Article DOI

10.1534/g3.119.400850

Licence

Exports