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Supplemental Material for Rechtsteiner et al., 2019

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posted on 2019-03-25, 15:52 authored by Andreas Rechtsteiner, Meghan E. Costello, Thea A. Egelhofer, Jacob M. Garrigues, Susan Strome, Lisa N. Petrella

Figure S1 contains ChIP signals of H3K4me3 and H3K9me2 on genes regulated in by synMuv B proteins. Figure S2 contains heat maps of ChIP-seq data. Figure S3 contains box-plots of gene body and promoter peak widths, and contains venn diagrams comparing H3K9me2 ChIP-seq data between genotypes. Figure S4 contains data on the overlap of ChIP from LIN-15B and the DREAM complex. Figure S5 contains enrichment analysis of genes with called H3K9me2 promoter peaks for genes with different categories of expression. Figure S6 contains the chromosomal distributions of genes with germline expression. Figure S7 contains the chromosomal distributions of genes with H3K9me2 promoter peaks or gene body peaks in lin-35and lin-37 mutants. Figure S8 contains H3K36me3 signals over genes in wild-type and synMuv B mutant L1s. Figures S9 contains H3K4me3 signals over genes in wild-type and synMuv B mutant L1s. Figure S10 contains H3K4me3 signals vs H3K9me2 signals in lin-35 and lin-37 mutants. Figure S11 contains comparison between HPL-2 promoter binding and H3K9me2 promoter peak locations. Table S1 is a spreadsheet containing the genes with peak calls of H3K9me2. Table S2 has all of the p-values on Fisher’s exact tests for genes with a called H3K9me2 gene body peak from Figure 1. Table S3 has all of the p-values on Fisher’s exact tests for genes with a called H3K9me2 promoter peak from Figure 1.

History

Article title

Repression of Germline Genes in Caenorhabditis elegans Somatic Tissues by H3K9 Dimethylation of Their Promoters

Manuscript #

GENETICS/2018/301878R1

Article DOI

10.1534/genetics.118.301878

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