Supplemental Material for Pitchers et al., 2019

Supplemental Table and Figures in PDF format. Supplemental Materials and methods. Supplemental tables in .xlsx format.<br><br><div>File S1. Supplementary Materials and Methods. </div><p> </p> <p><br></p><p>File S2. Means and S.D. of PC scores by lab and sex of fly, eigenvectors of the combined data set, and the estimated among-line genetic variance-covariance matrix in a 40-dimensional and phenotypic (97-dimensional) spaces. </p> <p> </p> <p><br></p><p>File S3. Significant SNPs from the MANOVA and LASSO analyses.</p><p><br></p> <p> </p> <p>File S4. Enriched biological process gene ontology categories. Table consists of the modified output from the WebGestalt analysis of the 479 genes implicated by the LASSO-significant SNPs. <br></p><p><br></p> <p> </p> <p>File S5. Genes studied in RNAi knockdown experiments, the quantiles of maximum correlations out of 580 random comparisons, and the angles between effect vectors and the first 5 PCS of the combined data set. </p> <p> </p> <p><br></p><p>File S6. Vectors correlations>0.5 between dictionary knockdown vectors and LASSO SNP vectors. <b><br></b></p><p><b><br></b></p><p>The File BoythLabs_Wings_28Oct.csv is the Procrustes superimposed data from both labs (22923 wings) from the DGRP used for the primary GWAS described in this study.<br><br>The zip file Genotyping-5019.001-01.csv.zip contains all of the genotyping data for the replication analysis for the ME-NC cohort as described in the paper.<br><br>slid_lmdata_DGRP+NC&ME.dat contains all of the wings from both the DGRP and the NC & ME replication set jointly superimposed.<b><br></b></p>