Supplemental Material for Kawamura and Maruyama, 2019 Kazuto Kawamura Ichiro N Maruyama 10.25387/g3.8150759.v2 https://gsajournals.figshare.com/articles/dataset/Supplemental_Material_for_Kawamura_and_Maruyama_2019/8150759 Fig S1. Photos of Edge Assay; Table S1. Number of screened genomes and isolated mutants; Fig S2. Maximum velocity and travel distance of isolated mutants; Fig S3. <i>ix241</i> and <i>ix243</i> worms show progressive locomotor decline after four backcrosses; Table S2. Lifespan Analysis; Fig S4. Greater reduction in total locomotor healthspan compared to lifespan in <i>ix243</i> worms; Table S3. Development times of isolated mutant strains; Fig S5. Strategy to identify causative mutation site; Table S4. Remaining mutations in <i>ix243</i> mutant strains; Fig S6. Wild-type <i>elpc-2</i> gene rescues progressive decline in locomotor ability of the <i>ix243</i> mutant strain; Fig S7. The Elongator complex is required to maintain adult locomotor ability; Fig S8. Expression pattern of <i>elpc-2</i> transcriptional GFP fusion; Fig S9. <i>tut-1(tm1297)</i> mutant shows progressive decline in locomotor ability; Table S5. Development times of <i>tut-1(tm1297)</i> and <i>elpc-2(ix243)</i>;<i>tut-1(tm1297)</i> mutants; Fig S10. Amino acid alignment of <i>C. elegans</i> ELPC-2 and human ELP2; Table S6. Strain list; Table S7. Primer list.<div><br></div><div>Figure legends and descriptions of tables are shown in "Description of Supplementary figures and tables.docx". </div> 2019-06-25 14:05:19 Aging effects C. elegans, Caenorhabditis elegans locomotor ability Genetics