Supplemental Material for Jain, 2019 JainKavita 2019 <p>All details included in supplemental.tex</p><p><br></p><p><strong> </strong> Figure S1: Fixation probability for <em>N</em> = 6 × 10<sup>5</sup> when the beneficial effect<em> s<sub>b</sub></em> is varied. The other parameters are <em>s<sub>d</sub> </em>= 0.01 (top) and 0.002 (bottom) with <em>u<sub>d</sub> </em> = 5<em>s<sub>d</sub></em>, <em>U<sub>d</sub></em> = <em>u<sub>d</sub></em>. The data from stochastic simulations (•) with errorbars representing the standard deviation, and by numerically calculating (1) (◦) and (5) (△) are shown.</p><p><br></p><p>Figure S2: Fixation probability for <em>N</em> = 6 × 10<sup>5</sup> when the beneficial effect<em> s<sub>b</sub></em> is varied. The other parameters are <em>s<sub>d</sub></em> = 0.01, <em>u<sub>d</sub></em> = 5<em>s<sub>d</sub></em>, <em>U<sub>d</sub></em> = 2<em>u<sub>d</sub></em> (top) and <em>s<sub>d</sub></em> = 0.002, <em>u<sub>d</sub></em> = 5<em>s<sub>d</sub></em>, <em>U<sub>d</sub></em> = 5<em>u</em><sub><em>d</em> </sub>(bottom). The data from stochastic simulations (•) with errorbars representing the standard deviation, and by numerically calculating (1) (◦) and (5) (△) are shown.</p><p><br></p><p></p><p></p><p>Figure S3: Expected substitution rate <em>E</em>[<em>k<sub>b</sub></em>] and average fixed selection co-efficient <em>E</em>[<em>s<sub>b</sub></em>] for <em>N</em> = 2 × 10<sup>5</sup> when the average beneficial effect <em>s</em>¯<sub><em>b</em></sub> is varied. The other parameters are <em>s<sub>d</sub></em> = 0.01, <em>u<sub>d</sub></em> = 5<em>s<sub>d</sub></em>, <em>u<sub>b</sub></em> = 5 × 10<sup>−7</sup>. The data from numerical simulations (•) and numerical integration of (12) and (17) using quadratic approximation (5) (⊕) and analytical expression (9) (◦) are shown.</p><p></p><p></p><p><br></p><p><br></p>