Supplemental Material for Hivert et al., 2018 HivertValentin LebloisRaphaƫl J. PetitEric GautierMathieu VitalisRenaud 2018 File S1 contains the detailed mathematical derivations of the model; Table S1 provides a comparison of pairwise <i>F</i><sub>ST</sub> estimates; Table S2 shows the effect of unequal sampling on pairwise <i>F</i><sub>ST</sub> estimates; Table S3 shows the effect of variable coverage on pairwise <i>F</i><sub>ST</sub> estimates; Figure S1 shows pairwise estimators of <i>F</i><sub>ST</sub>; Figure S2 shows the precision and accuracy of our estimator of <i>F</i><sub>ST</sub> as a function of pool size and coverage, with varying experimental error rate; Figure S3 shows the precision and accuracy of naive estimators of <i>F</i><sub>ST</sub> for Pool-seq data; Figure S4 shows the precision and accuracy of alternative estimators of <i>F</i><sub>ST</sub> with varying pool size, for various levels of differentiation.<br>