Supplemental Material for Hamza et al., 2020
Akil Hamza
Maureen R.M. Driessen
Erik Tammpere
Nigel J. O'Neil
Philip Hieter
10.25386/genetics.11573229.v1
https://gsajournals.figshare.com/articles/dataset/Supplemental_Material_for_Hamza_et_al_2020/11573229
<p>Figure S1 contains complementation assays for the
nonessential CIN genes. Figure S2 contains complementation assays of two-subunit
yeast complexes. Figure S3 contains growth curve assays for testing hFEN1
inhibitors in MMS. Figure S4 contains growth curve assays for testing hFEN1
inhibitors in HR-deficient strains. Figure S5 contains growth curve assays
assessing overexpression of h<i>FEN1</i> in
yeast. Table S1 lists primers used for CRISPR-mediated insertion and deletion.
Table S2 lists plasmids and strains used in study. Table S3 lists all candidate
complementation pairs tested in study. Table S4 compares our list of complementation
pairs to literature sources.</p>
2020-01-14 19:17:33
Human-yeast cross-species complementation
chromosome instability
chemical inhibitors
Fen1
cancer targets
Cancer
Cell Biology
Evolutionary Biology
Genetics
Molecular Biology